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Old 09-13-2008, 06:12 AM   #1
Chris Parson
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Default cannibinoids promote brain growth



http://www.ted.com/index.php/talks/d...your_fate.html

Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects.
J Clin Invest. 2005 Nov;115(11):3104-16. Epub 2005 Oct 13.

From the Abstract: The hippocampal dentate gyrus in the adult mammalian brain contains neural stem/progenitor cells (NS/PCs) capable of generating new neurons, i.e., neurogenesis. Most drugs of abuse examined to date decrease adult hippocampal neurogenesis, but the effects of cannabis (marijuana or cannabinoids) on hippocampal neurogenesis remain unknown. This study aimed at investigating the potential regulatory capacity of the potent synthetic cannabinoid HU210 on hippocampal neurogenesis and its possible correlation with behavioral change. We show that both embryonic and adult rat hippocampal NS/PCs are immunoreactive for CB1 cannabinoid receptors, indicating that cannabinoids could act on CB1 receptors to regulate neurogenesis. This hypothesis is supported by further findings that HU210 promotes proliferation, but not differentiation, of cultured embryonic hippocampal NS/PCs likely via a sequential activation of CB1 receptors, G(i/o) proteins, and ERK signaling. Chronic, but not acute, HU210 treatment promoted neurogenesis in the hippocampal dentate gyrus of adult rats and exerted anxiolytic- and antidepressant-like effects. X-irradiation of the hippocampus blocked both the neurogenic and behavioral effects of chronic HU210 treatment, suggesting that chronic HU210 treatment produces anxiolytic- and antidepressant-like effects likely via promotion of hippocampal neurogenesis.

AND

In The Neuroscientist vol 13, no. 2, 109-114 (2007)
"The Endocannabinoid System and Neurogenesis in Health and Disease"

From the abstract: The endocannabinoid system exerts an important neuromodulatory function in different brain areas and is also known to be involved in the regulation of neural cell fate. Thus, CB1 cannabinoid receptors are neuroprotective in different models of brain injury, and their expression is altered in various neurodegenerative diseases. Recent findings have demonstrated the presence of a functional endocannabinoid system in neural progenitor cells that participates in the regulation of cell proliferation and differentiation. In this Research Update, the authors address the experimental evidence regarding the regulatory role of cannabinoids in neurogenesis and analyze them in the context of those pathological disorders in which cannabinoid function and altered neuronal or glial generation is most relevant, for example, stroke and multiple sclerosis. NEUROSCIENTIST 13(2):109—114, 2007.
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Old 09-13-2008, 09:51 AM   #2
Gozaimasu Stone
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Default Re: cannibinoids promote brain growth

is there any differentiation in these results between cannaboid plants naturally grown through photosynthesis and non-photosynthetic processes such as hydroponically manipulated/altered cannaboid plants?

Do your results come from the analysis of both processes?
If the results are different,what would be the differentiating factors and why?
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Old 09-13-2008, 10:20 AM   #3
bluestix
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Default Re: cannibinoids promote brain growth

Of course it does.


Why do you think it is illegal.


It's the best cure for Babylon's Disease.


The people in this world have a mind sickness.
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Old 09-13-2008, 03:57 PM   #4
FrostyMcunicron
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Default Re: cannibinoids promote brain growth

the brain releases natural cannibinoids.


On the other hand Cannabis Sativa has proven cancer preventing properties & if THC is present when a cell goes deficient it dies instead of doubling every time.. Perhaps in the Near future we will bare witness to a "Crimes against humanity" class action lawsuit against the USA GOV & every politician who knowingly continued prohibition in return $$ and power. The 1# drug dealer in the world IS the USA Gov. Monopoly anyone?
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Old 09-13-2008, 06:44 PM   #5
Chris Parson
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Default Re: cannibinoids promote brain growth

Quote:
Originally Posted by Gozaimasu Stone View Post
is there any differentiation in these results between cannaboid plants naturally grown through photosynthesis and non-photosynthetic processes such as hydroponically manipulated/altered cannaboid plants?
i don't know.

Quote:
Originally Posted by FrostyMcunicron View Post
the brain releases natural cannibinoids.
http://en.wikipedia.org/wiki/Cannabinoid_receptor

http://en.wikipedia.org/wiki/Endocan...docannabinoids

Quote:
On the other hand Cannabis Sativa has proven cancer preventing properties
http://www.redorbit.com/news/health/..._medical_uses/
Code:
Researchers presented tantalizing evidence that cannabinoid drugs
 can help treat amyotrophic lateral sclerosis, known as ALS or Lou Gehrig's
 disease, Parkinson's disease and obesity. Other researchers are studying 
whether the compounds can help victims of stroke and multiple sclerosis.
http://www.cpmc.org/professionals/re...ence/sean.html
Code:
In addition to Δ9-THC, cannabidiol (CBD), cannabinol (CBN) and 
cannabigerol (CBG) are also present in reasonable quantities in Cannabis. 
CBN has low affinity for CB1 and CB2 receptors, whereas the non-psychotropic 
cannabinoids, CBD and CBG, have negligible affinity for the cloned receptors. 
We have determined that these additional cannabinoids are also effective 
and inhibiting aggressive cancers.
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Old 09-19-2008, 06:53 PM   #6
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Default Re: cannibinoids promote brain growth

So, what you're telling me is, I shouldn't have quit?

I think a lot clearer, and faster off it, though. My lungs are happy too.

Based on my experiences, I'd say there's a lot of give and take with C.Sativa. It helped me with pain from an injury to my dura mater at C5-6 level, and also gave me more awareness of proprioception and kinesthesia in my left side(due to an old brain injury) which all helped in my physical rehab. But, cognitively speaking, it takes away a few IQ points, and some fine motor coordination.

It definitely shouldn't be illegal though. I think it helps more than it hinders.

I'm hoping that using the abbreviated Latin terminology doesn't alert the Google folks to an "adult" conversation here. Maybe we just have to come up with our own terminology for certain things here, that no one else uses.
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Old 09-19-2008, 07:24 PM   #7
bluestix
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Default Re: cannibinoids promote brain growth

Quote:
Originally Posted by Debugged View Post
But, cognitively speaking, it takes away a few IQ points, and some fine motor coordination.

Speak for yourself.
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Old 09-19-2008, 08:18 PM   #8
uboslav
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Default Re: cannibinoids promote brain growth

This is an extremely interesting topic for me, because I grew up in the heart of marijuana land on vancouver island. It for years has been extremely abundant here. All generations of life in this area seem to smoke on a regular basis.

Recently after about 15 years of smoking it day in and day out I decided to quit. I had discovered through access to my higher self through dowsing that it was not harming me, it was merely a distraction. Instead of worrying about my well being, I was worrying about getting stoned.

I went on to ask my pendulum so so many questions on the topic that what resulted is me quitting to concentrate on my well being. Once I did quit , I noticed that sitting at a computer for any length of time was very uncomfortable, eating food was nearly impossible for a few days, and going to bed at a decent time..forget it.

All of this has now passed and I seem to be back on track to my normal feelings and thought. But at the time when i was indulging in heavy smoke it was very fair to say that it motivated me. It was like I didnt want to learn anything unless I was freshly stoned. It definitely did spark brain activity for me. I do know another in my town who still is like this. Get him stoned and he will rebuild his truck from the ground up part by part. One of our friends use to call us motivated stoners.

So through first hand experience I would say YES weed does stimulate the brain in someway or another. I would like to hear other opinions on this. We are led to believe through mass propaganda that getting stoned will make u stupid. I do not believe this. I think it just effects different people in different ways.
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Old 09-19-2008, 11:54 PM   #9
ADAM KADMON
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Default Re: cannibinoids promote brain growth

Good ol'MJ~

If you are anything like me, you've experimented your fair share with Marijuana and psychedlics... and you have been back and forth between 'quitting' and restarting more than once.

However, I think learning to discipline yourself into using only once or twice per week, at the appropriate time of day amplifies it's effectiveness and medicinal qualities 100 fold. The reason being is this:

When you can control your usage, you enjoy the emotions of order, self-discipline and control IN ADDITION to the irrefutable medicinal qualities MJ has to offer. Instead of experiencing the negative emotions that stem from a lack of self control, it actually gives you an opportunity to excite the opposite positive emotions of balance!

When you use MJ often enough that your body is giving you negative feedback, it's time to back off and objectively concentrate on the proper usage for you. This takes maturity. This times compassion and understanding towards yourself. And it takes a teaspoon of willpower to follow-through with your decision.

Some people find it easier to just cut it of their lives totally when they are not using it. Others find it easier to cope by making it a daily routine. It's been my experience that the most beneficial time in my life, was only after employing self discipline with it's usage.

That's not something a MJ fanatic wants to hear. But deep down, they know it to be true. I'm just reminding you of what you likely already know to be true.

Adam K.
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Old 09-20-2008, 12:11 AM   #10
bluestix
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Default Re: cannibinoids promote brain growth

Higher Doses


“I now have absolute proof that smoking even one marijuana cigarette is equal in brain damage to being on Bikini Island during an H-bomb blast.”

--Ronald Reagan quotes (American 40th US President (1981- 89), 1911-2004)


People have a right to get stoned. They have a right to think and explore their own minds. This is as intimate a part of their being as their sexuality. Any culture which mitigates that is clearly afraid of a full and fair and open dialogue about what reality is and what real human values ought to be.

--Terence McKenna



"You can look at the harm caused by free radicals as biological friction or biological rust and the endocannabinoid system minimizes the impact of that and directly acts as an antioxidant as well as modifying the biochemistry in a way that minimizes the impacts," said Melamede outside court Thursday, likening endocannabinoids to humans like oil is to cars. He said if you don't have lubrication in your car, your car breaks. In the human body, the damage comes in the form of age-related diseases.

"I'm saying what science has now shown is that marijuana and cannabinoids are effective anti-aging agents which means that they are effective in minimizing the onset and the severity of age-related illnesses which include cognitive dysfunction things like Alzheimers, cardiovascular disease be it heart attacks, strokes, or clogged arteries," he said.

But while it does not work for every one, cannabis can also help those people with auto-immune diseases and cancer.

Melamede explained that you would have to take 40,000 times the therapeutic dose before causing harm to your body. But the therapeutic index for aspirin is 15 to one.

"It's extremely safe," said Melamede of marijuana, noting the overdose amount would equal 40,000 joints.

"And you die happy," added Judge Don Sperry during a rare moment of levity in Thursday's testimony.





And finally --- Marijuana cures cancer:

RUN FROM THE CURE - The Rick Simpson Story
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Old 09-20-2008, 12:56 AM   #11
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Default Re: cannibinoids promote brain growth

Rick Simpson is a good man and he helped many people free of charge. I am a firm believer that a lot of the drugs should be legal, well the non manufactured ones at least. Mushrooms, cannabis and other "drugs" have been used for thousands of years and none of them really became illegal until after Alcohol prohibition. My guess is that with all the people they hired to fight the alcohol war were going to loose their job after it was made legal so they needed a new enemy. The war on drugs and the war on terror were two wars that were never made to be won, just to make tons of money and destroy our freedom!
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Old 09-20-2008, 02:24 AM   #12
Toymachines
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Default Re: cannibinoids promote brain growth

Hell ya. I would say it promotes brain growth, it at least makes you think farther outside the box. But, it is a distraction, a blessed distraction...
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Old 09-20-2008, 02:52 AM   #13
ForsakenFalcon
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Default Re: cannibinoids promote brain growth

It's hard to say because at first it does make You think out side the box and I must admite it sure did help Me pass My year 10 english and maths exsame's it made 3hours fly by like nothing elles and at the time the maths question's were allmost like decodeing so it wasn't as boreing.

However like someone allready said after awhile it get's to the point of when You don't want to do anything while sober eithen the thing's You previously "Loved" as in hobbie's and such.

I never avise anyone to smoke weed however if You so choice to like any drug You got to take personal responsibility on a new level geting high on eithen hullsagine's so long as Your doing it for the right reason's in term's of a learning cerve then You'r realy doing no harm, People whom use drug's then go stealing mugging and eithen killing then crying to the court's
"It was the drug's man I had no idear what I was doing blah blah blah"
it's utter bull **** each and every time Iv been high on anything Iv all ways knew My action's still had consiquences and that alot of what I was experienceing was due to I was high I never once disreguarded that fact.
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Old 09-20-2008, 03:36 AM   #14
Dantheman62
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Default Re: cannibinoids promote brain growth

Amen

Last edited by Dantheman62; 09-20-2008 at 04:54 AM.
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Old 09-20-2008, 01:53 PM   #15
Theresa
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Default Re: cannibinoids promote brain growth

I know someone who is a "motivated stoner" also. But he is also completely self centered, totally disassociated from others in relationship and completely distracted with "phenomenon based" spiritual experience.

I tried to keep up with him (daily smoker) because it was the only way to relate to him, but couldn't come close. After smoking daily for 25 years, he could smoke a LOT. I can't. not even a little. I'm ALREADY a channeler-I became completely unproductive on it. He, however, is very productive, owns his own business, makes a ton of money.

What spirit told me is that pot does give people access to INTERDIMENSIONAL information, which is exciting and distracting to say the LEAST.

But on the negative side, it DIMINISHES one's connection to their HIGHER SELF, the only level of spiritual information that really matters. In other words, it's an intellectual's distraction of choice, I would say. its a HUGE distraction.

Just because it activates the brain don't mean it evolves it, brothers....
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Old 09-20-2008, 09:57 PM   #16
Orion11
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Default Re: cannibinoids promote brain growth

doesnt mean it doesnt help it evolve either.

really jus here to bump the thread. lol

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Old 09-21-2008, 01:19 AM   #17
Chris Parson
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Default Re: cannibinoids promote brain growth

yeah don't smoke all day every day, kids
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Old 10-12-2008, 06:15 AM   #18
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Default Re: cannibinoids promote brain growth

Quote:
Originally Posted by bluestix View Post
Speak for yourself.
Basically, this research kind of debunks the idea that smoking weed kills brain cells.

I say it depends on the person and how much they smoke. I know some people are very smart, very brilliant but they cannot kick their weed habit long enough to do something with the talent they have.
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Old 10-12-2008, 04:36 PM   #19
Dantheman62
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Default Re: cannibinoids promote brain growth

O.K. Here I go, I've been a daily smoker for 32 years straight, yes 32 years 16 hours a day or more, I'm a self proclaimed expert on the subject and for sure it hurts the dreaming process and being able to remember dreams. It should not be illegal, but alcohol should!. I recently quit(1 week ago) just so I could get a decent job(**** tests) and my dreams have come back and now I can remember them better. It does motivate sometimes, and sometimes not depending on frame of mind or what's going on that day. It is a great social barrier breaker and allows one to get along with other fellow smokers regardless of age differences. It does however dominate sometimes like when you run out and are looking for more, but I've actually lost a couple pounds in the last week just by not getting the munchies so bad. Anyway that's my input and if anybody wants to talk more just pm me, I love to talk about sticky buds! woohoo! PEACE , Dan P.S. I'm 46 so I started at 14 wow and if I had all that money I spent on it I'd be retired LOL.
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Old 10-15-2008, 08:04 AM   #20
ForsakenFalcon
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Default Re: cannibinoids promote brain growth

it's odd every few year's or so i'll gain this sudden strong instinct to quit weed for a few weeks or a few months and adventuraly it just seem's to keep comeing back lol... =/

it's allmost like my soul uses it to sleep and stops it when it wants to be focused lol =P
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Old 10-25-2008, 03:32 AM   #21
Brinty
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Default Re: cannibinoids promote brain growth

Damn it! I need new glasses. At a quick glance, I thought this thread was titled "CANIBALS Promote Brain Growth."
I was on the verge of rushing next door to eat our neighbour when my wife pointed out my mistake. Just as well - he's pretty fat and I've got a cholesterol problem.
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Old 10-27-2008, 08:57 AM   #22
Luminari
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Default Re: cannibinoids promote brain growth

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Originally Posted by Brinty View Post
Damn it! I need new glasses. At a quick glance, I thought this thread was titled "CANIBALS Promote Brain Growth."
I was on the verge of rushing next door to eat our neighbour when my wife pointed out my mistake. Just as well - he's pretty fat and I've got a cholesterol problem.
awesome
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Old 10-27-2008, 09:20 AM   #23
TranceAm
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Default Re: cannibinoids promote brain growth

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Originally Posted by End_Times012 View Post
Basically, this research kind of debunks the idea that smoking weed kills brain cells.

I say it depends on the person and how much they smoke. I know some people are very smart, very brilliant but they cannot kick their weed habit long enough to do something with the talent they have.
Not in this corporate land, where only a study from ITT counts for something and not the talents people have...
If you look in history, there were (And Are!) lots of people doing very creative things.

I would almost go out on a limb to state, that there were some primates long ago near a field of hemp that caught fire, they breathed some of the smoke, and one had a thought pop up in his mind.. What if we go to the other side of the river and survive that way instead of running our *** of to stay in front of the approaching fire?. Homo First thought was born... But I can't state that, so I won't. We were "created".

Symbiosis is a close ecological relationship between the individuals of two (or more) different species. Sometimes a symbiotic relationship benefits both species, sometimes one species benefits at the other's expense, and in other cases neither species benefits.

Just say no;-)

Last edited by TranceAm; 10-27-2008 at 09:27 AM.
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Old 10-27-2008, 12:30 PM   #24
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Default Re: cannibinoids promote brain growth

Not only for the smoking but also:

http://projectavalon.net/forum/showt...7965#post37965

Oh, I must say: After 38 years of smoking on a daily basis I gave it up and although I enjoyed it I never regretted giving it up because my head is clearer and my dreams are back again.

Last edited by Peer; 10-27-2008 at 12:34 PM.
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Old 10-27-2008, 11:15 PM   #25
Bleep!
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Exclamation Cannibinoids promote Paranoia

Cannabis may promote paranoia and depression in some people.

There are enough paranoid and depressed people here already.

Moderation in all things.

(wise moderation)

Last edited by Bleep!; 10-29-2008 at 03:17 AM.
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