I'm always delighted when the pineal gland is mentioned.
It's part of the endochrinal system in the body which adepts referenced
in ceremonial ritual thousands of years ago.
This article
http://www.hermetics.org/stavish/Secret_Fire.html
is a contemporary guide to accessing the spinal fire which relates to this.
True alchemy is the study of combining body and soul to form spirit or immortality and the pineal gland is an important part of this.
This book
http://www.sacred-texts.com/eso/cdg/index.htm#contents
is one of many that reference more ancient texts which relate to this.
I'm going to research the metagene now.
Cheers, Chris.