I have many, many links and .pdf's from the world of nanotech.
I will throw one in here every now and then, when i see it on the "New Posts" search.
To start:
http://www.lightsources.org/cms/?pid=1002622
New treatment could render staph completely harmless
Quote:
The multi-institutional team exploited a chemical pathway that allows the Staph bacterium to defend itself against an immune response. The researchers showed that a compound (BPH-652) originally designed to lower cholesterol blocks a key enzyme in that pathway, weakening the organism’s defenses and allowing the body’s immune cells to prevail against the infection.
|
For a listing of the types of diseases than can negatively impact us due to staph:
http://mednote.co.kr/11BACTERIAL.htm
Quote:
STAPHYLOCOCCUS AUREUS:
MANIFESTATIONS:
Cutaneous:
Furuncle: Boil, infected hair follicle.
Carbuncle: Boil resulting from cluster of furuncles.
Bacteremia: Targets kidneys, lungs, hearts, bone. Possible coagulopathy.
The first thing you will see is an isolated abscess in an organ -- a clue that systemic S. Aureus infection is occurring.
You may also see petechial hemorrhages in fingernails, toes, and digits.
Endocarditis can result.
Septic embolus can break off of the vegetations and go to a distal peripheral artery (such as finger) to cause an infarct.
Osteomyelitis can also result. Used to occur in children. Septic arthritis occurs in adults, associated with heroin IV-needle use.
Scalded Skin Syndrome: Bullous lesions leading to desquamation in infants.
It is a result of the toxin Exfoliatin. No bugs are found in the lesion.
It will heal without scarring, if treated carefully and not spread.
Toxic Shock Syndrome: Result of TSS-Toxin.
High-grade fever, headache, myalgia, hypotension, rash, diarrhea.
Food Poisoning: Abdominal cramps, diarrhea, vomiting, 2-12 hours after eating. Staph Aureus is the most common cause of food poisoning in the U.S.
Associated with mayonnaise kept at room temperature, such as at a picnic.
Results from Enterotoxins A-E
VIRULENCE:
COAGULASE: Staph Aureus is Coagulase (+) and thus virulent. Coagulase Negative Staph (CNS) are far less virulent.
Catalase, Fibrinolysins, Hyaluronidase.
Methicillin-Resistant Staph Aureus (MRSA): Must be treated with Vancomycin.
Coagulase-Negative Staph (CNS): Less virulent. S. Saprophyticus causes UTI's in young females.
|